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Key Mechanisms Studied in Animal Models Reduction of specific inflammatory cytokines in tissue samples Support for blood vessel formation near injury sites Possible influence on gut lining repair Shifts in immune cell behavior toward tissue repair Interaction with growth factor pathways involved in healing 3

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In a later study, the authors investigated oxidative DNA damage between AD patients with and without delirium tremens, using 8-OHdG as a biomarker in AD patients with and without delirium tremens and reported that AD patients with delirium tremens have higher serum 8-OHdG levels than those without delirium tremens, suggesting that higher oxidative stress carries a greater risk of the occurrence of delirium tremens [60]